Author: Michael

For centuries, a small piece of dark fabric lay buried on the Central Asian steppes, alongside the remains of a young woman. Brown, brittle and barely distinguishable from the surrounding soil, the fragment looked like little more than a patch of dirt. Under a microscope, however, the cloth told a different story. It had traveled an extraordinary distance to reach the grave, centuries before the trade routes later known as the Silk Road began to take shape. A Scrap of Cloth in a Steppe Grave The fragment was recovered from the Karatumma cemetery in southeastern Kazakhstan’s Almaty region. Dating to…

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Drug companies maintain large libraries of chemical compounds that can be screened for potential use in the development of new pharmaceuticals. One class of these compounds, sulfonamides, is used in antibiotics and in drugs to treat type 2 diabetes, hypertension and inflammation. Thousands of these sulfonamides exist in these libraries, but their use beyond their initial purpose is limited because they are difficult to chemically modify.

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